Gene-edited 2013 Bat Cornavirus Ratg13

Coronavirus has mutated RaTG13

(two main versions now) by ...


View: https://www.youtube.com/watch?v=NtWVY2DW2nc

 

View: https://www.youtube.com/watch?v=JI8HgorLj0M&list=UUZyk2NYx6wGnpoJ7ApTxWKg

 

Evidence that the SARS-CoV-2 virus is genetically engineered
Published: 12 May 2020


A scientist argues that the evidence for a “natural” origin
for the virus is fabricated. Report: Claire Robinson

An anonymous scientist[1] has published a detailed article
arguing that SARS-CoV-2, the virus causing the COVID-19 pandemic,
is a genetically engineered lab creation.
What’s more, the author argues that the particular bat coronavirus
from which SARS-CoV-2 is claimed to have naturally emerged
– dubbed RaTG13 – is a fabrication.

In other words, the author says the “natural origin”
for the virus was made up in a desperate attempt
to let those responsible for the lab escape off the hook.

According to the author, the fabrication was perpetrated by Shi Zhengli,
director of the Wuhan Institute of Virology (WIV) in China.

The WIV is only a few kilometres from the Wuhan seafood
and wildlife market that was initially blamed for the outbreak.

Zhengli has been dubbed by the media “the bat woman” for her role
in collecting bat viruses from the wild for her “gain-of-function” research.

“Gain-of-function” research seeks to make viruses more virulent or more transmissible
– for instance, making a virus airborne or better adapted to different host species.

Such research is not necessarily intended for bioweapons development
– it’s supposedly intended to help develop vaccines and therapeutics
for virus epidemics and for basic research on the behaviour of viruses.

But it’s been fiercely criticized for decades by some scientists
for posing huge risks to public health in return for little or no benefit.

In fact, the author of the new article does suggest that SARS-CoV-2
was developed as a bioweapon, though he doesn’t suggest
that it was deliberately released as one.

The new article, titled, “RaTG13 – the undeniable evidence that the
Wuhan coronavirus is man-made”, appears on the “Nerd has Power” blog.

The blog site doesn’t identify the author, so we’ll call him or her “Nerd”,

and assume he’s male, for the purposes of this article.

The article is technical in parts but Nerd does his best
to make it accessible to the layperson by explaining
every step of his logic, at the same time as giving definitions
of scientific terms.

In our experience, he succeeds, though non-scientists
may need to read the technical parts with close attention,
possibly more than once!

The new article brings solid scientific evidence to the row
that is raging over the origin of SARS-CoV-2.

Some scientists have said that the virus is the result of natural evolution
in animal or human hosts. But others have said that while natural emergence
is possible, it’s also not possible to rule out a lab escape,
either of a natural virus obtained from the wild for research,
or even of a genetically engineered virus.

As Nerd points out, all publications arguing for a natural origin for SARS-CoV-2
rely on a single piece of evidence – the sequence of a purported natural
bat coronavirus named RaTG13.

RaTG13 looks like a “close cousin” of SARS-CoV-2
– the two are 96% identical throughout the whole sequence of the viral genome.

If RaTG13 is a natural virus, SARS-CoV-2 very likely also comes from nature
and must share a recent common ancestor with RaTG13.

Indeed, it has been argued by those in support of the natural origin
of SARS-CoV-2 that the virus arose by the mutation of RaTG13
in animal and/or human hosts.

But there’s one major problem with the natural origin theory, according to Nerd:

The RaTG13 virus isn’t real. It doesn’t exist as a “live” sample,
only as a sequence of letters in a computer, which only in January this year,
after the COVID-19 outbreak hit, was uploaded into a public database.

Nerd believes that this sole evidence of its existence, its genetic sequence,
was fabricated. And, he says, the major suspect in the fabrication is Shi Zhengli.

We summarise below Nerd’s technical argument that SARS-CoV-2,
as originally found in Wuhan, China, was genetically engineered.

However, we strongly encourage readers to go to his full article, t
o look at the graphs that illustrate his argument, and to check out his linked sources.

Nerd’s argument is being taken seriously by many well qualified commentators,
both on Twitter and in the Comments section of his original posting here.

His updated post, which takes account of comments and corrections
he’s received from readers, is here.
---
Summary of Nerd’s argument that SARS-CoV-2 is genetically engineered

1) Many mutations in natural evolution are single DNA or RNA nucleotide substitutions;
that is, a change of a single base unit (nucleotide) in the order of the base units
that constitutes the genetic material of the organism.

(Note: The genetic material of coronaviruses is RNA, not DNA.)

These random single nucleotide mutations
within a protein-coding region of the genetic material
of an organism can have one of two outcomes.

Either it can have no effect on the genetic code
and thus no effect on the order
of amino acids in the corresponding protein
– this is known as a “synonymous mutation”;
or the single nucleotide change can alter the genetic code,
leading to a change in the amino acid sequence of the protein
for which it encodes, conferring in turn new properties to the protein

– this is known as a “non-synonymous mutation”.

2) There are strict rules that govern natural evolution
through random single nucleotide mutation.

In particular, typically the ratio
between the number of synonymous mutations
and that of non-synonymous mutations should be around 5:1;
that is, 5 times more synonymous mutations
than non-synonymous arise through this process.

In other words there should be an amino acid change
with every 6th single nucleotide mutation.

3) If we consider the natural rates and patterns of mutational changes
between two bona fide native bat coronaviruses identified by a lab in China
that has a military background, ZC45 and ZXC21,
everything is as predicted, in line with what
we know about how viruses evolve in nature.

The changes are consistent with what is expected when two lineages
closely relate to each other evolutionarily and the differences
in their sequences are the results of random mutations.

The ratio between the number of synonymous mutations
and that of non-synonymous mutations is around 5:1.

4) But a comparison between SARS-CoV-2
and its purported close relative RaTG13
shows a pattern that’s completely inconsistent
with natural evolution through single nucleotide substitution.

The synonymous/non-synonymous mutation ratio is 44:1
– wildly divergent from the 5:1 ratio expected from a natural evolution.

5) Comparing SARS-CoV-2 and RaTG13, the whole spectrum of RNA sequence
and amino acids have a very high similarity in every genomic region
except in the S2 (Spike 2) half of the spike protein
– which is very different.

The S2 spike protein region doesn’t follow the evolutionarily predicted
and observed frequency of synonymous and non-synonymous mutation rates
for coronaviruses.

Although there are 90 nucleotide differences
there are only two amino acid substitutions
rather than the 15 that would be expected.

Thus there are far fewer amino acid substitutions
compared with what should happen naturally.

6) A safe conclusion to the above points is that,
between SARS-CoV-2 and RaTG13, at least one is non-natural.

If one is natural, then the other one must not be.

It’s also possible that neither of them came from nature.

7) The part of a virus that determines how good it is at infecting humans
is the receptor binding domain (RBD) located in the S1 region
of the spike protein
located on the surface of the virus.

The RBD dictates whether or not the virus can bind to the ACE2 receptor
on the surface of human cells and thereby infect humans.

This is the “business part” of the virus. If it’s not right, it won’t infect humans.

If it is right, it will.

8) If indeed RaTG13 is a fabrication, what are the bona fide bat viruses t
hat are most closely related to the Wuhan SARS-CoV-2 virus
and thus could be its “parents”?

By comparing amino acid and nucleotide sequences,
Nerd identifies the two bat coronaviruses reported in the scientific literature,
ZC45 and ZXC21, as the closest fits. ZC45 and ZXC21
are also remarkably similar to each other, with a 97% sequence identity.

9) A comparison between the amino acid sequences
of the Wuhan SARS-CoV-2 virus as originally described
and the ZC45 and ZXC21 viruses shows a remarkable identity
in all but one crucial region.

In the majority of the virus there is 95% amino acid sequence identity,
but there is one crucial region where they are strikingly dissimilar,
with only 69% identity.

That is the S1 region of the spike protein that harbours the RBD.

Given the very high identity in all other regions of the SARS-CoV-2 virus
when compared with ZC45 and ZXC21, it is highly improbable
that such a huge difference in just the S1 part of the spike protein
of SARS-CoV-2 could have arisen naturally over the timespan
in which they are supposed to have co-existed in nature.

10) The other striking result of a comparison
between SARS-CoV-2 and ZC45/ZXC21
relates to another component, the E protein.

The E protein is a structural protein of coronaviruses
that can tolerate a large number of mutations
without any negative impact on function.

This is highlighted by the fact that even after just two months
after the outbreak of the COVID-19 pandemic,
mutations in the E protein of SARS-CoV-2 were identified.

However, when comparing the original SARS-CoV-2 virus
with the ZC45/ZXC21 bat viruses,
they have a 100% identical E protein amino acid sequence.

Given the high mutation rate observed in SARS-CoV-2
(and in coronaviruses in general), and given the fact that mutations
can occur anywhere in the virus genome,
including in the E protein region,
it makes no biological sense that the original SARS-CoV-2 virus
would have a 100% identical E protein amino acid sequence
to the ZC45/ZXC21 bat viruses.

11) Both the above basic biological observations strongly indicate
that the only way that SAS-CoV-2 can be so dissimilar
in the S1 region of the spike protein (crucial to human infectivity),
yet identical in a far less crucial component such as the E protein,
is through intentional design (genetic manipulation in the lab)
and not by natural mutation and selection in animal and human hosts.

12) The above information strongly points to SARS-CoV-2
being constructed based on one or both of the two bat viruses,
ZC45 and ZXC21, rather than the purported RaTG13.
---
Intention

Based on the above information, in GMWatch’s interpretation,
the intention of these genetic manipulations would be to determine
which amino acid changes are required in the RBD of bat viruses
for them to gain infectivity in human cells.

We do not share Nerd’s conclusion that the original SARS-CoV-2
was necessarily developed as a bioweapon, though there’s no proof that it wasn’t.

It is equally likely to have been developed for study purposes
and/or in order to help develop therapies or vaccines
for current or future coronavirus pandemics.
Shi Zhengli’s role

There is also the question of Shi Zhengli’s involvement.

Nerd poses a series of questions that must awaken suspicion
in anyone familiar with the naked ambition that characterizes t
he virus gain-of-function area of scientific research.

Nerd asks: If RaTG13 were a bona fide natural bat coronavirus
discovered in the wild in 2013, as Shi Zhengli claims,
given its "star quality" regarding the high potential to infect humans,
why didn’t Shi rush to publish its sequence at the time in a prestigious journal?

After all, this is what she had done previously with other bat coronaviruses,
Rs3367 and SHC014, which share considerable sequence similarity with SARS.

Why did she wait until January 2020,
when the public row began about the possible lab origin
of SARS-CoV-2, before publishing the sequence?[2]

Nerd’s implication is that, with speculation mounting about the possible
lab origin of SARS-CoV-2, and the WIV being a chief suspect,
Shi scrambled to come up with some sort of “evidence”
to show that the virus had a natural origin
and thus was nothing to do with her lab.

That “evidence” consisted of the fabricated sequence of RaTG13.
Why 2013?

If we accept Nerd’s conclusion that RaTG13 is a fabrication,
why would Shi and her collaborators claim it was discovered way back in 2013,[3]

as opposed to more recently? Nerd doesn’t go into this,
but GMWatch believes that two possible reasons are:

1) To avoid awkward questions about why no live sample
of RaTG13 is available, enabling us to confirm its real existence
– after all, 2013 is a long time ago.

2) To give sufficient time for RaTG13 to plausibly naturally mutate
and emerge as SARS-CoV-2, thus supporting the “natural origin”
hypothesis for the COVID-19 epidemic.
Why the delay?

GMWatch follows Nerd in finding Shi Zhengli’s delay
in publishing the sequence of RaTG13 very curious
to say the least and we understand why he regards it as highly suspicious.

In our view, such work, once published, would be universally acclaimed
as of immense public health import and potentially worthy of the Nobel Prize.

If RaTG13 is real, it’s not the kind of thing that a scientist of Shi’s
standing would normally keep under wraps for years.

As any scientist can tell you, they are driven by the desire to be the first
to announce a new discovery and to bask in the peer recognition
and glory that this brings – unless, of course, secrecy was mandated
because the plan was to use RaTG13 in some way that could not be disclosed,
for example, as the basis for developing a bioweapon.

Personal ambition apart, Shi Zhengli is at fault either way,
if RaTG13 is real or if it’s fake.

If RaTG13 is real, Shi’s failure to immediately report this discovery
appears to be an act of extreme negligence that has recklessly
endangered public health.

In accord with proper scientific conduct in the public interest,
Shi was morally obliged to promptly announce her discovery
of RaTG13 and thus put world health authorities on alert
as to the possibility of this bat virus acquiring the relatively few mutations
needed to convert it to a human pathogen, thus leading to a new SARS pandemic.

If RaTG13 is fabricated, she would be guilty of scientific fraud,
apparently committed to cover up an act of negligence in the form
of her lab’s construction and accidental release of SARS-CoV-2.

In our view, the evidence presented above shows
that there is an urgent need for a credible
and independent international investigation
into the origins of SARS-CoV-2 and the roles played by Shi Zhengli,
the Chinese government, and the US bodies that helped fund the virus research
at the WIV, including the National Institutes of Health and the EcoHealth Alliance.
---
Notes

1. Some of our readers have voiced concerns at the fact
that we are taking seriously certain evidence (e.g. this)
about SARS-CoV-2’s origins despite the fact that it is anonymously authored.

While we support full transparency and accountability in science,
we understand that powerful interests and strong emotions
are involved in the current situation.

Therefore we are not surprised that some commentators
are afraid to put their names to their views.

This may be particularly the case with Nerd, who,
judging by his use of Chinese on his blog site,
may be a Chinese citizen.

In his article, he strongly accuses the “Chinese Communist Party”
for responsibility for SARS-CoV-2’s emergence.

Because we want to get the evidence on SARS-CoV-2
out into the open and because we believe that scientists
have as much of a right to “stay safe” as the rest of us,
we will continue to publish scientific articles
on the topic even when the authors feel that they have to remain anonymous.

2. The sequence of BtCoV/4991 RdRp – a fragment of a bat virus genome
(370 nucleotides) – was published by Shi Zhengli
and colleagues in 2016, four years before RaTG13.

As far as the fragment goes, it is identical to the RaTG13 sequence
published in Jan 2020.

However, this does not affect Nerd’s argument that RaTG13 is a fake.

As the commentator “Simen” says on Nerd’s blog site,
“The existence of RaBtCoV/4991 actually does not prove anything.

The sequence is only 370bp in length and everything else [was]
still not published until 27-JAN-2020.…

Notably, if what they claim was true on the S protein,
we should [have] already seen the RBD of RaTG13 being published before.

We didn't.

Therefore, we cannot rule out fabrication/manipulation
for the rest of RaTG13/RaBtCoV/4991.

Without being able to rule out such fabrication/manipulation,
the argument that RaTG13 is invalid as ‘evidence’ for a ‘natural’ origin
of SARS-CoV-2 is still… valid….”
It is a mystery as to why Shi and colleagues only published
a tiny fragment of this virus genome.

The procedure used to obtain the sequence of this RdRp
gene fragment would have provided them with the entire sequence
of the virus.

Thus the rest of the sequence information appears to have been withheld.

3. In a 2016 paper, Shi describes the collection of samples
from a mineshaft that led to the isolation of the bat virus BtCoV/4991.

Peter Daszak of the EcoHealth Alliance has stated on Twitter
that BtCoV/4991 is the same virus from the same sample as RaTG13.

https://www.gmwatch.org/en/news/lat...hvoNK5mc_6yu7jp-oGcKWFyHqIQZsUsBJj6iBwKrkGKQQ

 

FOUND THIS; but; haven;t been able to prove it

Italy has allegedly discovered covid is not a virus, but a bacterium.

It clots the blood and reduces the oxygen saturation from dispersing

throughout the body.

They went against the World Health Organization's \"law\"
that no bodies be autopsied.

When Italian Ministry of Health ordered many autopsies,
they found the blood was clotted in all of the patients veins.

They immediately started using aspirin 100mg and a coagulant medication.

And have had immense success. 14,000 people were released
from the hospital as \"healthy\" and covid free.

Italy is demanding Bill Gates and the World health Organization
be held accountable for \"crimes against humanity\"
for misleading, misdirecting, and withholding life saving information
from the world, which cost the lives of thousands.

Ventilators and ICU units were not necessary.

A mandated vaccine is not necessary.

Covid19 is a bacterium, easily

treated with aspirin and coagulant.

Spread the word! Make this global.

Hopefully our president will learn about this
and do something about it! Before we lose all of our constitutional freedoms.
Copy and pasted

STILL CHECKING if IT IS TRUE

 

SUSAN @13LiNESofSPiRiT@13LiNESofSPiRiT
·11h
@davidicke 1357=16/7 and, 1510=7

In 1510, an acute respiratory disease emerged in Asia
before spreading through North Africa and Europe
during the first chronicled, inter-regional flu pandemic
generally recognized by medical historians and epidemiologists.
Influenza-like illnesses had been documented in Europe
since at least Charlemagne, with 1357's outbreak
the first to be called influenza, but the 1510 flu pandemic

@13LiNESofSPiRiT @davidicke

i got more info than just this; let me search for it

 

HELLOOOOO.... THERE IS NO 'VIRUS' - DAVID ICKE DOT-CONNECTOR VIDEOCAST https://www.bitchute.com/video/zUqVV62hRSIQ/ @davidicke

"There are forms of bioweaponized 'cold' or 'flu' aka cornavirus or cornavirus
~so, this is a bioweapon , and, these types of pandemnics go very far back in history...
1510,
1918-1919-1920 h1n1 spanish flu,
1957- 1958 asian flu h2n2
1968-1969 hong kong flu h3n2
1977 h1n1 russian flu
2009 swine flu 2009-2010 h1n1-09 ,
and; then; there is typicals flus A SERIES: a/h3n2, a/h1n1, B SERIES...
THERE was seen 3 + 4 = 7 and 12 form of cornavirus
INTERESTING 3 + 4 + 7 +12 =19

within days OF ANNOUNCING
THE CORNAViRUS
people noticed that 'it was already printed on a lysol bottle'
and; very fast
it's name changed to "covid 19"

 

HELLOOOOO.... THERE IS NO 'VIRUS' - DAVID ICKE DOT-CONNECTOR VIDEOCAST https://www.bitchute.com/video/zUqVV62hRSIQ/ @davidicke

"There are forms of bioweaponized 'cold' or 'flu' aka cornavirus or cornavirus
~so, this is a bioweapon , and, these types of pandemnics go very far back in history...
1510,
1918-1919-1920 h1n1 spanish flu,
1957- 1958 asian flu h2n2
1968-1969 hong kong flu h3n2
1977 h1n1 russian flu
2009 swine flu 2009-2010 h1n1-09 ,
and; then; there is typicals flus A SERIES: a/h3n2, a/h1n1, B SERIES...
THERE was seen 3 + 4 = 7 and 12 form of cornavirus
INTERESTING 3 + 4 + 7 +12 =19

withink days OF ANNOUNCING
THE CORNAViRUS
people noticed that 'it was already printed on a lysol bottle'
and; very fast
it's name changed to "covid 19"


Gene-edited 2013 Bat Cornavirus Ratg13 | Page 2 | Cosmogenesis - Library of Akbar Ra in Alexandria Thuban (cosmosdawn.net)

https://www.cosmosdawn.net/forum/threads/gene-edited-2013-bat-cornavirus-ratg13.8774/page-2
and;
page 1
https://www.cosmosdawn.net/forum/threads/gene-edited-2013-bat-cornavirus-ratg13.8774